chart on in sickness and in health

   This is a project that we created based on facts from two families.  This is a chart to show how the disease traveled through the family tree.

1.What would a pedigree of Greg and Olga’s families look like?

They are shown above.  There are differences in the charts that you see, such as different diseases but as you see in both charts, the diseases skip generations.

2. Do autosomal dominant disorders skip generations? It is possible if there is a recessive trait but it the traits are domanate it will not skip.

3. Could Greg or his mother be carriers of the gene that causes myotonic dystrophy? It is not possible because the gene is domanite and it would show up on them to.

4.Is there a possibility that Greg’s aunt or uncle is homozygous for the myotonic dystrophy (MD) gene? It isn't possible because the other two sibblings don't have the disease.

5.What is the possibility that Greg and Olga’s children could inherit the MD gene? No since Greg’s mom and Greg did not have the gene and Olga didn't show signs of it there is no way there kids could develope this gene.

6.What are the hallmarks of an autosomal recessive trait? The characteristics of autosomal traits are that they skip generations and are present when there are no other dominate traits to take it over or two parents withe recessive genes have a child.

7.What does consanguineous mean? Why is this concept especially important when discussing recessive genetic disorders?  The dictionary deffanition is "Relating to or denoting people descended from the same ancestor". This is so important because it can show us what diseases come through our families.  Many genes can be traced through a family tree.

8.What is it about the inheritance pattern of factor VIII deficiency seen in Greg and Olga’s pedigree that point toward it not being an autosomal recessive trait? Since factor VIII is not in all the families and siblings it shows it being autosomal recessive trait. It is not an autosomal trait because thechance of boys and girls getting factor VIII or Hemophilia is not equal.